Prions act completely unrelated to heat. Actually they act unrelated to most factors which is why curing them is so hard.

They just kinda exist as a misfolded protein that does nothing until it bumps into something compatible, all on a size scale comparable to shooting a grain of sand into space and expecting it to hit a random planet. In fact you likely already have prions floating in your body but the chance of them hitting anything to fold is so small it might aswell be nothing (These are actually the cause of Alzheimers)

There is no intent or complex functions to it. It only gets worrying when you ingest more prions, increasing the probabilities